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Whilst lack of MBD2 results in lessened figures of T regulatory (Treg) cells, MBD2 null mice astonishingly tend not to build autoimmunity. In individuals, elevated levels of MBD2 and world-wide demethylation in CD4+T cells have already been noticed in a number of autoimmune Conditions, including SLE.19 20 nonetheless, substantial effort and hard wo
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